Impact of Gongronema Latifolium on Serum Selenium and Lipid Fractions in Wistar Rats
Keywords:
Gongronema latifolium, Lipid fraction, selenium, arterosclerosisAbstract
The highly nutritious leaf of the edible vegetable Gongronema latifolium is meaty and delicious. The purpose of this study was to ascertain how Gongronema latifolium may affect the serum selenium level and lipid profile in wistar rats. Four sets of six adult male rats each were created from the twenty-four adult rats, all weighing between 100 and 120 grams. As a healthy control group, Group A was used. For 28 days, the Gongronema latifolium extract was given to groups B, C, and D at dose concentrations of 40 mg/kg, 80 mg/kg, and 120 mg/kg body weight, respectively. One-way analysis of variance (ANOVA) was used to analyze the data, and then the student's t-test was used. When compared to the control group, the administration of Gongronema latifolium resulted in a substantial decrease in low density lipoprotein, triglycerides, and total cholesterol (P<0.05). As serum In comparison to the control, there was a significant rise in serum selenium and high density lipoprotein. The alterations in the lipid profile and selenium were contingent on the dosage. This finding suggests that gongronema latifolium extract may be helpful in the management of arteriosclerosis.
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