International Journal of Medical Science and Pharmaceutical Research

Transgender individuals face a unique constellation of challenges that intersect social, psychological, and structural domains. Central to their experiences are relationship disruptions, difficulties in emotion regulation, and pervasive everyday discrimination, each compounding the risks of adverse mental health outcomes. Despite growing social visibility, many transgender individuals grapple with family rejection, strained romantic relationships, and social isolation, all of which erode their psychological resilience and exacerbate feelings of alienation. 

This review paper draws on secondary data from peer-reviewed journals and empirical studies published between 2019 and 2025, synthesizing contemporary research on the psychosocial stressors impacting transgender individuals. Special emphasis is placed on how maladaptive emotion regulation strategies and chronic experiences of microaggressions intensify mental health vulnerabilities. The analysis further highlights the buffering effects of supportive relationships, adaptive coping strategies, and resilience mechanisms in fostering well-being. The paper critically evaluates existing interventions and underscores the need for inclusive, affirming, and culturally sensitive approaches to mental health care. This review serves as a comprehensive resource for mental health professionals, advocates, and policymakers striving to dismantle systemic barriers and promote psychological health and social integration among transgender populations.

Transgender individuals, relationship issues, emotion regulation, discrimination, resilience, mental health, inclusive interventions.

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