International Journal of Medical Science and Pharmaceutical Research

Background: Globally, even across all regions and income groups, the majority of child mortality occurred during the earlier age with 85 percent of the 6.3 million deaths in 2017 occurring in the first five years of life. Measuring how many children   die each year and why they died along with measuring how diseases and injuries are affecting children  is one of the most important means for assessing the effectiveness of a country’s health system. Cause-of-death statistics   even among all age groups helps health authorities determine the focus of their public health actions. They may be used to determine which preventive and medical curative measures or which focus in research might increase the life expectancy of the population.

Aim: To determine the pattern and the determinants  of deaths among pediatric patients in DUFUTH between March 2022 to June 2025.

Objectives:

1. To determine the social demography of pediatric patients in DUFUTH
2. To determine the pattern and frequency  and determinants of mortality among pediatric age group in DUFUTH
3. To determine if possible the variable contributing factors to death among hospitalized children in DUFUTH.

Result: Mortality among children in DUFUTH was recorded as 17.9%(52) out of 291 mortalities recorded between March 2022 to June 2025 with male  preponderance, accounting for  55.8%(29) and female 44.2%(23). Severe malaria ranked the highest  among the determinants of death among children accounting for 30.7%(16), followed by  neonatal sepsis accounting  for 26.9%(14). Anaemic heart failure accounted for 19.1%(10), while perinatal asphyxia and acute gastroenteritis accounted for 9.6%(5) and 5.7%(3) respectively. Low birth weight, severe malnutrition, febrile seizure and acute watery diarrhoea accounted for 2% (1) respectively. Death was more rampant between  age range of  0-1 year  with a frequency of 50%(26).  This is followed by age 2-5years   which recorded 21.2% (11) deaths.  Ages 6-10 recorded 19.2%(10) deaths while 11-17years recorded 5(9.6%) deaths respectively.2024 saw the highest number of mortality in children accounting for 42.3% of the total mortality. Year 2023 had 32.7%, while  year 2022 had the least death frequency accounting for 9.6% while the first quarter of 2025 accounted for 15.4%.Across all the years of study except 2025,most of the deaths occurred in the evenings, between the hours of 5-11pm while year 2025 recorded highest death in the morning hours( 12am to 12noon).

Conclusion: Despite the significant progress made in curbing  mortalities among children across the world, this ugly event has remained bothersome and unabated with mortalities among children still at alarming rate especially under 5 and among neonate. Any serious nation who wants to make a giant  stride in heath of her citizens must developed practical interventional approach that can yield effective and enduring results.

mortality, sepsis, children, policy, death.

1. Asghar, R.M., Sharif, M., Saheel, K., Ashraf, R.R., Hussain, A. Pattern of Paediatric Mortality of hospitalized patients in a Tertiary Care Hospital, Rawalpindi. Journal of Rawalpindi Medical College. 30 Sep. 2020; 24(3): 260-263. DOI: https://doi.org/10.37939/jrmc.v24i3.1388.
2. Dr. Khalid ObaidMohsin. Leading causes of death for patients admitted to the Al-Sadder teaching hospital since 2006 to June 2012 in Miasn providence / Iraq. Misan Journal For Academic Studies. 
3. Okoroiwu HU, Uchendu KI, Essien RA (2020) Causes of morbidity and mortality among patients admitted in a tertiary hospital in southern Nigeria: A 6 year evaluation. PLoSONE 15(8): e0237313. https://doi.org/10.1371/journal. pone.0237313
4. Chiwar H. M.1, Bulama H. U.2, Ahmad U. M.2, Kolo F. A.2. exploring the patterns and characteristics of death in northeastern nigeria: a study of university of maiduguri teaching hospital mortality cases. Chiwar et al. (2023) BJMLS, 8(2): 34 – 44
5. Also U, Gwarzo GD. Patterns of morbidity and mortality among neonates seen in a tertiary hospital. Sahel Med J 2020;23:47-50.
6. Abdul-Khaliq A. Sallam, FCPS, DCH. Causes of child mortality in Sallam.Yemen … www.smj.org.sa Saudi Med J 2005; Vol. 26 (7).
7. Institute for Health Metrics and Evaluation (IHME). Global Burden of Disease 2021: Findings from the GBD 2021 Study. Seattle, WA: IHME, 2024.
8. Eilerts Julio Romero Prieto Jeffrey W. Eaton Georges Reniers. Age patterns of under-5 mortality in sub Saharan Africa during 1990‒2018: A comparison of estimates from demographic surveillance with full birth histories and the historic record. volume 44, article 18, pages 415-442 published 5 march 2021 https://www.demographic-research.org/Volumes/Vol44/18/ DOI: 10.4054/DemRes.2021.44.18
9. Ezeonwu BU, Chima OU, Oguonu T1, Ikefuna AN1, Nwafor I. Morbidity and Mortality Pattern of Childhood Illnesses Seen at the Children Emergency Unit of Federal Medical Center, Asaba, Nigeria. Annals of Medical and Health Sciences Research | Sep-Oct 2014 | Vol 4 | Special Issue 3 |
10.  I. O. George, B. A. Alex-Hart, A. I. Frank-Briggs. Mortality Pattern in Children: A Hospital Based Study in Nigeria. InternatIonal journal of BIomedIcal science. www.ijbs.org Int J Biomed Sci vol. 5 no. 4 December 2009 
11. EcheyIjezie*, Frances S. Okpokowuruk . Mortality audit in the paediatrics department of the University of Uyo teaching hospital, Uyo, Nigeria. International Journal of Research in Medical Sciences Ijezie E et al. Int J Res Med Sci. 2016 Feb;4(2):615-620 www.msjonline.org .
12. Ochora M, Kyoyagala S, Kyasimire L, Akambasisa M, Twine M, Ahmed M, et al. (2025) Patterns and predictors of mortality in the first 24 hours of admission among children aged 1–59 months admitted at a Regional Referral Hospital in South Western Uganda. PLoSONE 20(1): e0312316. https://doi.org/10.1371/journal. pone.0312316 
13. David B. Olawade, PHa,b, Ojima Z. Wada, PhDc, Nicholas Aderinto, MBBSd,* , AderonkeOdetayo, PHe, Yusuff Adebayo Adebisi, MScf, Deborah Tolulope Esan, PhDg, Jonathan Ling, PhDh. Factors contributing to under-5 child mortality in Nigeria A narrative review. Medicine (2025) 104:1www.md-journal.com
14. Robert Black, Amherst Simon Cousens,  Trevor Croft,, ICF Michel Guillot, Bruno Masquelier, Jon Pedersen, Fafo. United Nations Inter-agency Group for Child Mortality Estimation (UN IGME), ‘Levels & Trends in Child Mortality: Report 2018, Estimates developed by the United Nations Inter-agency Group for Child Mortality Estimation’, United Nations Children’s Fund, New York, 2018L evels& Trends in Child Mortality Report 2018 Estimates developed by the UN Inter-agency Group for Child Mortality Estimation. 
15. Hallie Eilerts Julio Romero Prieto Jeffrey W. Eaton Georges Reniers. Age patterns of under-5 mortality in sub Saharan Africa during 1990‒2018: A comparison of estimates from demographic surveillance with full birth histories and the historic record. demographic research journals volume 44, article 18, pages 415-442 published 5 march 2021 https://www.demographic-research.org/Volumes/Vol44/18/ DOI: 10.4054/DemRes.2021.44.18
16. Hao Tran K, Vo-Van NL, Nguyen-Thi KH, Le-Thy PA, Nguyen HS. Neonatal Morbidity and Mortality in a Neonatal Unit in a Vietnamese Hospital. Iranian Journal of Neonatology. 2022 Apr: 13(2). DOI: 10.22038/IJN.2022.59669.2132
17. OmarKarlsson,  PhD; RockliKim, ScD; Andreas Hasman,DPhil;S.V.Subramanian,PhD. AgeDistributionofAll-CauseMortalityAmongChildrenYoungerThan5Years in Low-and Middle-Income Countrie. Jama NetworkOpen.2022;5(5):e2212692.doi:10.1001/jamanetworkopen.2022.12692
18. Jason H. Choi,1,2,3*ThomasE.Tanner,3 Michelle D. Eckerle,2,4 Jane S. Chen,5 Emily J. Ciccone,6 Griffin J. Bell,7 Flexon F. Ngulinga,8 Elizabeth Nkosi,9 Rachel S. Bensman,2,4 Heather L. Crouse,3 Jeff A. Robison,10 Msandeni Chiume,9 and Elizabeth Fitzgerald,11 on behalf of the Pediatric Alliance for Child Health Improvement in Malawi at Kamuzu Central Hospital and Environs (PACHIMAKE) Consortium. Mortality by Admission Diagnosis in Children 1–60 Months of Age Admitted to a Tertiary Care Government Hospital in Malawi. Am.J. Trop. Med. Hyg., 109(2), 2023, pp. 443–449 doi:10.4269/ajtmh.22-0439 Copyright © 2023 The author(s)
19. AishwaryaTekam*, SharmilaRamteke, RashmiRanda. Risk factors associated with mortality in children with severe pneumonia. International Journal of Contemporary Pediatrics Tekam A et al. Int J ContempPediatr. 2023 Jul;10(7):1013-1018 http://www.ijpediatrics.com
20. Prem Chand Meena1, Anil Solanki2, R.K. Verma3, Mahesh Soni4. Pattern of Unnatural Death in Paediatric Age Group: A Retrospective Study at Tertiary Care Centre. Available online on http://www.ijcpr.com/ International Journal of Current Pharmaceutical Review and Research 2025; 17(2); 983-987
21. Pramila Ramawat1, Nilesh Jain2. Morbidity and mortality profile of children admitted in pediatric department – A single center study. Asian Journal of Medical Sciences | May 2021 | Vol 12 | Issue 5
22. Rahman, Md. Sazedur and Rahman, Md. Saidur and Rahman, Md. Ashfikur. Determinants of death among under-5 children in Bangladesh. Online at https://mpra.ub.uni-muenchen.de/93511/ MPRA Paper No. 93511, posted 01 May 2019 21:16 UTC. 10 January 2019
23. Odo Romanus Chukwuemeka. patterns and determinants of infant and childhood mortality in developing countries. the nigerian academic forum vol. 1 no. 2, november, 2001
24. *Shaza A Fadel, AgbessiAmouzou. Child and adolescent deaths: a call for strengthening mortality surveillance systems. www.thelancet.com/lancetgh Vol 10 March 2022 www.thelancet.com/lancetgh Vol 10 March 2022.