International Journal of Medical Science and Pharmaceutical Research

Background: Bronchial asthma is among the most prevalent chronic respiratory diseases of childhood globally and contributes substantially to recurrent morbidity, school absenteeism, emergency healthcare visits, and impaired quality of life. India contributes approximately 12.9% of global asthma cases, and data from coastal southern India on clinical phenotyping and associated factors remain limited. 

Objectives: To describe the clinical profile and severity pattern of bronchial asthma among children aged 5–15 years and to identify associated allergic, familial, environmental, and perinatal risk factors. 

Methods: A hospital-based study was conducted enrolling 290 children aged 5–15 years with bronchial asthma diagnosed by standard clinical criteria. Data on demographics, age at onset, family history, allergic manifestations, birth weight, feeding practices, and triggering factors were collected using a structured proforma. Asthma severity was classified per NAEPP-EPR-3 criteria. 

Results: Intermittent asthma was the most common severity category (132/290, 45.5%), followed by mild persistent (84/290, 28.9%), moderate persistent (64/290, 22.1%), and severe persistent asthma (10/290, 3.4%). Severe persistent asthma was confined to children aged 10–15 years. Early-onset asthma (≤3 years) was present in 130 (44.8%) children. Family history of asthma was reported in 154 (53.1%) participants. Allergic rhinitis was the commonest associated allergic condition. Seasonal variation (81.4%), upper respiratory tract infection (80.0%), and dust exposure (74.5%) were the leading triggering factors. 

Conclusion: Childhood bronchial asthma in this hospital-based cohort was predominantly intermittent or mild persistent and was strongly associated with atopic manifestations, positive family history, and environmental triggers. Early identification, caregiver education, and reduction of preventable exposures are essential for reducing asthma-related morbidity among children.

Bronchial asthma, children, allergic rhinitis, clinical profile, environmental exposure, India, pediatric asthma, risk factors

1. Global Initiative for Asthma. Global strategy for asthma management and prevention, 2024 update. Fontana (WI): GINA; 2024. Available from: https://ginasthma.org/
2. 2. World Health Organization. Asthma [Internet]. Geneva: WHO; 2026 [cited 2026 May 23]. Available from: https://www.who.int/news-room/fact-sheets/detail/asthma
3. Stern J, Pier J, Litonjua AA. Asthma epidemiology and risk factors. Semin Immunopathol. 2020;42(1):5-15.
4. Ellwood P, Asher MI, Rutter CE, Bissell K, Castro-Rodriguez JA, Chiang CY, et al. Prevalence, time trends and treatment practices of asthma in India: the Global Asthma Network study. ERJ Open Res. 2022;8(2):00528-2021.
5. Pal R, Dahal S, Pal S. Prevalence of bronchial asthma in Indian children. Indian J Community Med. 2009;34(4):310-6.
6. Awasthi S, Kalra E, Roy S. Prevalence and risk factors of asthma and wheeze in school-going children in Lucknow, North India. Indian Pediatr. 2004;41(12):1205-10.
7. Chhabra SK, Gupta CK, Chhabra P, Rajpal S. Risk factors for development of bronchial asthma in children in Delhi. Ann Allergy Asthma Immunol. 1999;83(5):385-90.
8. Ahmadiafshar A, Taghiloo D, Esmailzadeh A, Falakaflaki B. Rhinitis and asthma in children: comorbidity or united airway disease? Curr Pediatr Rev. 2014;10(4):275-81.
9. Urbano FL. Review of the NAEPP 2007 Expert Panel Report (EPR-3) guidelines. J Manag Care Pharm. 2008;14(1 Suppl A):41-9.
10. Qureshi UA, Bilques S, Nisa K, Qureshi MA. Epidemiology of bronchial asthma in school children (6-13 years) in Srinagar. Lung India. 2016;33(2):167-73. 
11. Kumar GS, Roy G, Subitha L, Sahu SK. Prevalence of bronchial asthma and its associated factors among school children in urban Puducherry, India. J Nat Sci Biol Med. 2014;5(1):59-62.
12. Sharma SB, Bansal G, Soni GL, Sharma M. Prevalence of asthma in urban school children in Jaipur. Indian Pediatr. 2012;49(10):835-6.
13. Liang PH, Chiang BL, Fu LS, Chiang LC, Lin YJ, Lin KH. Clinical characteristics of childhood asthma according to age at onset. J Microbiol Immunol Infect. 2006;39(5):414-8.
14. Padem N, Saltoun C. Classification of asthma. Allergy Asthma Proc. 2019;40(6):385-8. 
15. Staikūnienė J, Vaitkaitienė E, Ryliškienė K. Connecting the airways: current trends in united airway diseases. Front Med (Lausanne). 2026;12:1369695.
16. Ripabelli G, Sammarco ML, Grasso GM, Fanelli I, Capriotti T, Mosca A, et al. Asthma prevalence and risk factors among children and adolescents living around an industrial area. BMC Public Health. 2013;13:1038.
17. Xu XF, Li YJ, Sheng YJ, Liu JL, Tang LF, Chen ZM. Effect of low birth weight on childhood asthma: a meta-analysis. BMC Pediatr. 2014;14:275.